Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 12/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 11/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11081655 | 0.84 | SLC6A4 (0.48) | SLC22A1SLC6A4SLC6A2OPRM1CHRM2 | |
| SCHEMBL11491769 | 0.82 | SLC22A1 (0.46) | SLC22A1SLC6A4SLC6A2OPRM1CHRM2 | |
| SCHEMBL11487162 | 0.81 | SLC22A1 (0.47) | SLC22A1SLC6A4SLC6A2OPRM1CHRM2 | |
| SCHEMBL11248009 | 0.78 | SLC22A1 (0.43) | SLC22A1SLC6A4SLC6A2OPRM1CHRM2 | |
| SCHEMBL11491011 | 0.72 | SLC6A4 (0.44) | SLC22A1SLC6A4SLC6A2OPRM1CHRM2 | |
| SCHEMBL11085421 | 0.70 | ALDH1A1 (0.40) | SLC22A1SLC6A4SLC6A2OPRM1CHRM2 | |
| SCHEMBL11651250 | 0.70 | SLC22A1 (0.50) | SLC22A1SLC6A4SLC6A2OPRM1CHRM2 | |
| SCHEMBL11651256 | 0.70 | SLC22A1 (0.50) | SLC22A1SLC6A4SLC6A2OPRM1CHRM2 | |
| SCHEMBL11492175 | 0.70 | SLC22A1 (0.50) | SLC22A1SLC6A4SLC6A2OPRM1CHRM2 | |
| SCHEMBL11492176 | 0.70 | SLC22A1 (0.50) | SLC22A1SLC6A4SLC6A2OPRM1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4448991-A | ANALGESICS | HOFFMANN-LA ROCHE INC. (US) | 1984-05-15 | — | — | US | disclosed |
| US-4336268-A | Cyclohexene derivative analgesics | HOFFMANN-LA ROCHE INC. (US) | 1982-06-22 | — | — | US | disclosed |