Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11487518 | 1.00 | SLC22A1 (0.50) | SLC22A1ALDH1A1HPGDTSHRSLC6A4 | |
| SCHEMBL11492176 | 1.00 | SLC22A1 (0.50) | SLC22A1ALDH1A1HPGDTSHRSLC6A4 | |
| SCHEMBL11651250 | 1.00 | SLC22A1 (0.50) | SLC22A1ALDH1A1HPGDTSHRSLC6A4 | |
| SCHEMBL11492175 | 1.00 | SLC22A1 (0.50) | SLC22A1ALDH1A1HPGDTSHRSLC6A4 | |
| SCHEMBL11254574 | 0.96 | ALDH1A1 (0.46) | SLC22A1ALDH1A1HPGDTSHRSLC6A4 | |
| SCHEMBL11491769 | 0.88 | SLC22A1 (0.46) | SLC22A1ALDH1A1HPGDTSHRSLC6A4 | |
| SCHEMBL11487162 | 0.78 | SLC22A1 (0.47) | SLC22A1ALDH1A1SLC6A4SLC6A2OPRM1 | |
| SCHEMBL11248709 | 0.78 | HSD11B1 (0.45) | TSHROPRM1KMT2A | |
| SCHEMBL11248009 | 0.75 | SLC22A1 (0.43) | SLC22A1ALDH1A1SLC6A4SLC6A2OPRM1 | |
| SCHEMBL9467270 | 0.75 | ALDH1A1 (0.54) | SLC22A1ALDH1A1HPGDTSHRSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4100166-A | Novel cis N-cyclopropylmethyl decahydroisoquinoline | ELI LILLY AND COMPANY (US) | 1978-07-11 | — | — | US | disclosed |