Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD3 | O94806 | 3/20 | 0.50 |
| ▸ | PRKCG | P05129 | 3/20 | 0.50 |
| ▸ | PRKCB | P05771 | 3/20 | 0.50 |
| ▸ | PRKCA | P17252 | 3/20 | 0.50 |
| ▸ | PRKCH | P24723 | 3/20 | 0.50 |
| ▸ | PRKCI | P41743 | 3/20 | 0.50 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.50 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.50 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.50 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.50 |
| ▸ | PRKD1 | Q15139 | 3/20 | 0.50 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.46 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.46 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.46 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.46 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.46 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.46 |
| ▸ | AKT1 | P31749 | 3/20 | 0.43 |
| ▸ | AKT2 | P31751 | 3/20 | 0.43 |
| ▸ | AKT3 | Q9Y243 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL11085675 | 1.00 | PRKD3 (0.50) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Phosphoric Acid SCHEMBL11081526 | 0.97 | PRKD3 (0.47) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Phosphoric Acid SCHEMBL11087945 | 0.93 | PRKD3 (0.56) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Phosphoric Acid SCHEMBL11078067 | 0.93 | PRKD3 (0.56) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL11084762 | 0.93 | PRKD3 (0.56) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL11086257 | 0.93 | PRKD3 (0.56) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL11079812 | 0.90 | PRKD3 (0.53) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Phosphoric Acid SCHEMBL11081350 | 0.87 | PRKD3 (0.42) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL11087685 | 0.85 | PRKCA (0.65) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL9670759 | 0.85 | PRKCA (0.65) | PRKD3PRKCGPRKCBPRKCAPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4444766-A | ANTITUMOR | BOEHRINGER MANNHEIM GMBH (DE) | 1984-04-24 | — | — | US | disclosed |