Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.63 |
| ▸ | CA1 | P00915 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
| ▸ | CA7 | P43166 | 1/20 | 0.63 |
| ▸ | CA9 | Q16790 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | NQO1 | P15559 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | YAP1 | P46937 | 1/20 | 0.49 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.49 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL755720 | 0.98 | CA12 (0.66) | CA12CA1CA2CA7CA9 | |
| Hydrochloric Acid SCHEMBL11519194 | 0.96 | CA12 (0.63) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6278422 | 0.92 | CA12 (0.59) | CA12CA1CA2CA7CA9 | |
| Methylene Chloride SCHEMBL28109052 | 0.91 | CA12 (0.58) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10412880 | 0.89 | CA12 (0.56) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8876368 | 0.85 | CA12 (0.51) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3494901 | 0.82 | CA12 (0.61) | CA12CA1CA2CA7CA9 | |
| SCHEMBL4527668 | 0.82 | CA12 (0.68) | CA12CA1CA2CA7CA9 | |
| SCHEMBL16376096 | 0.82 | CA12 (0.68) | CA12CA1CA2CA7CA9 | |
| SCHEMBL15801047 | 0.82 | KDM4E (0.61) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4489091-A | ESTERASE AND ANTIBODY INHIBITORS | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1984-12-18 | — | — | US | disclosed |
| US-4411911-A | Method of treating hyperlipidemia and inflammation with sulfonate derivatives | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1983-10-25 | — | — | US | disclosed |