SCHEMBL8876368

SCHEMBL8876368

CCOc1ccc(S(=O)(=O)O)cc1.O=S(=O)(O)c1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.51
CA1 P00915 2/20 0.51
CA2 P00918 2/20 0.51
CA7 P43166 2/20 0.51
CA9 Q16790 2/20 0.51
ALDH1A1 P00352 3/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
GAA P10253 3/20 0.47
NPSR1 Q6W5P4 1/20 0.47
CYP1A2 P05177 2/20 0.45
PKM P14618 2/20 0.44
NQO1 P15559 1/20 0.44
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
ALOX15 P16050 1/20 0.43
TSHR P16473 1/20 0.43
CYP2C19 P33261 1/20 0.43
MAPK1 P28482 2/20 0.42
LMNA P02545 1/20 0.42
MEN1 O00255 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL755720 0.87 CA12 (0.66) CA12CA1CA2CA7CA9
Hydrochloric Acid SCHEMBL11519194 0.85 CA12 (0.63) CA12CA1CA2CA7CA9
SCHEMBL11087708 0.85 CA12 (0.63) CA12CA1CA2CA7CA9
SCHEMBL6278422 0.82 CA12 (0.59) CA12CA1CA2CA7CA9
Methylene Chloride SCHEMBL28109052 0.80 CA12 (0.58) CA12CA1CA2CA7CA9
SCHEMBL10412880 0.79 CA12 (0.56) CA12CA1CA2CA7CA9
SCHEMBL14491287 0.74 CA1 (0.32) CA12CA1CA2CA7CA9
SCHEMBL6304613 0.73 CA1 (0.42) CA12CA1CA2CA7CA9
SCHEMBL8769185 0.73 GAA (0.56) CA12CA1CA2CA7CA9
SCHEMBL4527668 0.73 CA12 (0.68) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0792252-A1 MONOMERS AND COMPOSITION WHICH CAN BE CROSSLINKED AND CROSSLINKED POLYMERS Ciba SC Holding AG (CH) 1997-09-03 EP disclosed
WO-1996016008-A1 MONOMERS AND COMPOSITION WHICH CAN BE CROSSLINKED AND CROSSLINKED POLYMERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1996-05-30 WO disclosed