Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | ATM | Q13315 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6668500 | 0.77 | MAOB (0.52) | MTORRAB9AGRM7CYP3A4ALOX15 | |
| SCHEMBL21789003 | 0.74 | MTOR (0.58) | MTORRAB9AGRM7CYP3A4ALOX15 | |
| SCHEMBL6724867 | 0.74 | MTOR (0.58) | MTORRAB9AGRM7CYP3A4ALOX15 | |
| SCHEMBL27496285 | 0.72 | MTOR (0.37) | MTORRAB9AGRM7CYP3A4ALOX15 | |
| SCHEMBL27631395 | 0.71 | MTOR (0.43) | MTORRAB9AGRM7CYP3A4ALOX15 | |
| SCHEMBL4340485 | 0.69 | MAOB (0.42) | MTORRAB9AGRM7CYP3A4ALOX15 | |
| SCHEMBL8095249 | 0.69 | MTOR (1.00) | MTORRAB9AGRM7CYP3A4ALOX15 | |
| Hydrochloric Acid SCHEMBL3012657 | 0.68 | CYP3A4 (1.00) | MTORRAB9AGRM7CYP3A4ALOX15 | |
| SCHEMBL15591917 | 0.66 | GRM7 (0.65) | MTORRAB9AGRM7CYP3A4ALOX15 | |
| SCHEMBL22321648 | 0.66 | MTOR (0.65) | MTORRAB9AGRM7CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4448776-A | Method of using certain substituted aliphatic secondary amines or their salts for easing breathing | BUCHER KARL (CH) | 1984-05-15 | — | — | US | claimed |
| US-4448776-A | Method of using certain substituted aliphatic secondary amines or their salts for easing breathing | BUCHER KARL (CH) | 1984-05-15 | — | — | US | disclosed |