Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 1/20 | 1.00 |
| ▸ | RAB9A | P51151 | 1/20 | 1.00 |
| ▸ | GRM7 | Q14831 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.95 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.95 |
| ▸ | TSHR | P16473 | 1/20 | 0.95 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3012657 | 0.97 | CYP3A4 (1.00) | MTORRAB9AGRM7CYP3A4ALOX15 | |
| SCHEMBL10411095 | 0.90 | MTOR (0.81) | MTORRAB9AGRM7CYP3A4ALOX15 | |
| SCHEMBL11094399 | 0.87 | MTOR (0.75) | MTORRAB9AGRM7CYP3A4ALOX15 | |
| SCHEMBL8352681 | 0.85 | MTOR (0.74) | MTORRAB9AGRM7CYP3A4ALOX15 | |
| SCHEMBL1118824 | 0.85 | MTOR (0.74) | MTORRAB9AGRM7CYP3A4ALOX15 | |
| SCHEMBL27881139 | 0.85 | MTOR (0.74) | MTORRAB9AGRM7CYP3A4ALOX15 | |
| SCHEMBL7469490 | 0.85 | MTOR (0.74) | MTORRAB9AGRM7CYP3A4ALOX15 | |
| SCHEMBL11100772 | 0.85 | MTOR (0.74) | MTORRAB9AGRM7CYP3A4ALOX15 | |
| SCHEMBL2586127 | 0.85 | RAB9A (0.74) | MTORRAB9AGRM7CYP3A4ALOX15 | |
| SCHEMBL28729974 | 0.85 | MTOR (0.72) | MTORRAB9AGRM7CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4448776-A | Method of using certain substituted aliphatic secondary amines or their salts for easing breathing | BUCHER KARL (CH) | 1984-05-15 | — | — | US | claimed |
| US-20230126310-A1 | COMPOSITIONS FOR CORONAVIRUS INFECTION TREATMENT AND/OR PREVENTION | FRAUNHOFER GES FORSCHUNG (DE) | 2023-04-27 | — | — | US | disclosed |
| US-20230025575-A1 | PROCESS FOR PREPARING AMINES OVER A COPPER CATALYST | BASF SE (DE) | 2023-01-26 | — | — | US | disclosed |
| EP-4069418-A1 | PROCESS FOR PREPARING AMINES OVER A COPPER CATALYST | BASF SE (DE) | 2022-10-12 | — | — | EP | disclosed |
| US-20220244263-A1 | METHODS FOR TREATING SMALL CELL NEUROENDOCRINE AND RELATED CANCERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-08-04 | — | — | US | disclosed |
| CN-114746179-A | Method for producing amines on copper catalysts | 巴斯夫欧洲公司 | 2022-07-12 | — | — | CN | disclosed |
| EP-3039126-B1 | SMALL MOLECULE CELLULAR REPROGRAMMING TO GENERATE NEURONAL CELLS | THE J DAVID GLADSTONE INST A TESTAMENTARY TRUST ESTABLISHED UNDER THE WILL OF J DAVID GLADSTONE (US) | 2019-10-09 | — | — | EP | disclosed |
| US-20160250260-A1 | SMALL MOLECULE CELLULAR REPROGRAMMING TO GENERATE NEURONAL CELLS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-09-01 | — | — | US | disclosed |
| EP-3039126-A2 | SMALL MOLECULE CELLULAR REPROGRAMMING TO GENERATE NEURONAL CELLS | The J. David Gladstone Institutes, A Testamentary Trust Established under The Will of J. David Gladstone (US) | 2016-07-06 | — | — | EP | disclosed |
| WO-2015041809-A2 | SMALL MOLECULE CELLULAR REPROGRAMMING TO GENERATE NEURONAL CELLS | THE J. DAVID GLADSTONE INSTITUTES, A TESTAMENTARY TRUST ESTABLISHED UNDER THE WILL OF J. DAVID GLADSTONE (US) | 2015-03-26 | — | — | WO | disclosed |
| US-20100197800-A1 | Treatment and/or Prevention of Presbycusis by Modulation of Metabotropic Glutamate Receptor 7 | UNIVERSITY OF ANTWERP (BE) | 2010-08-05 | — | — | US | disclosed |
| US-20100197800-A1 | Treatment and/or Prevention of Presbycusis by Modulation of Metabotropic Glutamate Receptor 7 | UNIVERSITY OF ANTWERP (BE) | 2010-08-05 | — | — | US | disclosed |
| WO-2008131439-A1 | TREATMENT AND/OR PREVENTION OF PRESBYCUSIS BY MODULATION OF METABOTROPIC GLUTAMATE RECEPTOR 7 | HOUSE EAR INSTITUTE (US) | 2008-10-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230025575-A1 | PROCESS FOR PREPARING AMINES OVER A COPPER CATALYST | AOC2, SOD1, AOC3 | MTOR 3035/4885RAB9A 3433/4885GRM7 3728/4885 |
| US-20100197800-A1 | Treatment and/or Prevention of Presbycusis by Modulation of Metabotropic Glutamate Receptor 7 | GRM7, GRM3, GRM5 | MTOR 2034/4885RAB9A 2982/4885GRM7 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.