Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | HNF4A | P41235 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19681500 | 0.77 | ALDH1A1 (0.39) | ALDH1A1HSD17B10HPGDBCL2L1HDAC4 | |
| Formaldehyde SCHEMBL28305782 | 0.72 | ALDH1A1 (0.52) | ALDH1A1HSD17B10HPGDBCL2L1HDAC4 | |
| SCHEMBL29414275 | 0.71 | ALDH1A1 (0.58) | ALDH1A1HSD17B10HPGDBCL2L1HDAC4 | |
| SCHEMBL30332559 | 0.71 | ALDH1A1 (0.58) | ALDH1A1HSD17B10HPGDBCL2L1HDAC4 | |
| SCHEMBL29414264 | 0.71 | ALDH1A1 (0.58) | ALDH1A1HSD17B10HPGDBCL2L1HDAC4 | |
| SCHEMBL192419 | 0.71 | ALDH1A1 (0.58) | ALDH1A1HSD17B10HPGDBCL2L1HDAC4 | |
| SCHEMBL608537 | 0.71 | ALDH1A1 (0.58) | ALDH1A1HSD17B10HPGDBCL2L1HDAC4 | |
| SCHEMBL31498528 | 0.71 | ALDH1A1 (0.58) | ALDH1A1HSD17B10HPGDBCL2L1HDAC4 | |
| SCHEMBL29352295 | 0.71 | ALDH1A1 (0.58) | ALDH1A1HSD17B10HPGDBCL2L1HDAC4 | |
| Bicarbonate SCHEMBL10341263 | 0.69 | BCAT2 (0.58) | ALDH1A1HSD17B10HPGDBCL2L1HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4433152-A | ANTIINFLAMMATORY AGENT, ANTIALLERGEN OR ANTICOAGULANT | NIPPON CHEMIPHAR CO., LTD. (JP) | 1984-02-21 | — | — | US | disclosed |