Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11092704 | 0.78 | HSD17B2 (0.51) | LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL11090155 | 0.78 | CYP19A1 (0.50) | — | |
| SCHEMBL6779158 | 0.74 | ALDH1A1 (0.53) | KMT2ALMNAALDH1A1SMN1; SMN2GAA | |
| SCHEMBL6779114 | 0.74 | ALDH1A1 (0.53) | KMT2ALMNAALDH1A1SMN1; SMN2GAA | |
| SCHEMBL1858226 | 0.73 | ALDH1A1 (0.49) | KMT2AMEN1LMNARECQLALDH1A1 | |
| SCHEMBL11572125 | 0.72 | RECQL (0.49) | KMT2AMEN1LMNARECQLALDH1A1 | |
| SCHEMBL23727648 | 0.72 | SIRT6 (0.42) | KMT2AMEN1LMNARECQLALDH1A1 | |
| SCHEMBL28498083 | 0.70 | GRIA4 (0.41) | KMT2AMEN1LMNARECQLALDH1A1 | |
| SCHEMBL4191103 | 0.70 | HRH3 (0.47) | KMT2AMEN1LMNAALDH1A1SIRT6 | |
| SCHEMBL15744018 | 0.68 | HSD17B2 (0.42) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443616-A | Production of 3-pyrrolin-2-ones | THE PURDUE FREDERICK COMPANY (US) | 1984-04-17 | — | — | US | disclosed |