Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CCKBR | P32239 | 1/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11089341 | 1.00 | MEN1 (0.42) | MEN1KMT2ACCKBRCYP17A1LMNA | |
| SCHEMBL11688469 | 0.85 | MEN1 (0.43) | MEN1KMT2ACCKBRLMNAATM | |
| SCHEMBL11088546 | 0.83 | CYP17A1 (0.41) | CYP17A1DRD2ATMPRKDCLIPE | |
| SCHEMBL11088548 | 0.83 | CYP17A1 (0.41) | CYP17A1DRD2ATMPRKDCLIPE | |
| SCHEMBL11088554 | 0.83 | CYP17A1 (0.41) | CYP17A1DRD2ATMPRKDCLIPE | |
| SCHEMBL11084629 | 0.80 | CYP17A1 (0.36) | CYP17A1DRD2ATMPRKDCLIPE | |
| SCHEMBL11084630 | 0.80 | CYP17A1 (0.36) | CYP17A1DRD2ATMPRKDCLIPE | |
| SCHEMBL11684557 | 0.80 | KMT2A (0.46) | MEN1KMT2ACCKBRLMNAATM | |
| SCHEMBL4688423 | 0.79 | CTSS (0.50) | CYP17A1ATMPSMB8NAMPTPPARG | |
| SCHEMBL4688415 | 0.79 | CTSS (0.50) | CYP17A1ATMPSMB8NAMPTPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4464366-A | Cephem compounds having a terminal aminocarboxylic acid grouping and containing an azacyclyl(thio)ureido group | CIBA GEIGY CORPORATION (US) | 1984-08-07 | — | — | US | disclosed |