Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | LIPE | Q05469 | 1/20 | 0.34 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.34 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 3/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11084630 | 1.00 | CYP17A1 (0.36) | CYP17A1DRD2ATMPRKDCPTGDR2 | |
| SCHEMBL11730520 | 0.81 | FOLH1 (0.40) | ATM | |
| SCHEMBL11734338 | 0.81 | ALDH1A1 (0.34) | ATM | |
| SCHEMBL10759071 | 0.81 | SMN1; SMN2 (0.41) | ATM | |
| SCHEMBL10674321 | 0.81 | SMN1; SMN2 (0.41) | ATM | |
| SCHEMBL11729486 | 0.80 | CACNA2D1 (0.35) | — | |
| SCHEMBL11089341 | 0.80 | MEN1 (0.42) | CYP17A1DRD2ATMPRKDCLIPE | |
| SCHEMBL11088906 | 0.80 | MEN1 (0.42) | CYP17A1DRD2ATMPRKDCLIPE | |
| SCHEMBL11088546 | 0.80 | CYP17A1 (0.41) | CYP17A1DRD2ATMPRKDCPTGDR2 | |
| SCHEMBL11088548 | 0.80 | CYP17A1 (0.41) | CYP17A1DRD2ATMPRKDCPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4464366-A | Cephem compounds having a terminal aminocarboxylic acid grouping and containing an azacyclyl(thio)ureido group | CIBA GEIGY CORPORATION (US) | 1984-08-07 | — | — | US | disclosed |