Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27685597 | 0.89 | KMT2A (0.51) | ALDH1A1MAPTSMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL27685528 | 0.89 | NPC1 (0.51) | ALDH1A1MAPTSMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL27685565 | 0.89 | TDP1 (0.45) | ALDH1A1MAPTSMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL28769307 | 0.85 | L3MBTL1 (0.68) | ALDH1A1MAPTSMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL27704468 | 0.85 | L3MBTL1 (0.59) | ALDH1A1MAPTSMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL27704466 | 0.85 | PDPK1 (0.56) | ALDH1A1MAPTSMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL436598 | 0.84 | TSHR (0.53) | ALDH1A1MAPTSMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL31390336 | 0.83 | ALDH1A1 (0.48) | ALDH1A1MAPTSMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL14071758 | 0.83 | FFAR1 (0.52) | MAPTLMNAMAPK1CYP2C19 | |
| SCHEMBL3270768 | 0.83 | FFAR1 (0.52) | MAPTLMNAMAPK1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928827-B1 | PYRROLE DERIVATIVES AS THERAPEUTIC COMPOUNDS | MYRIAD GENETICS INC (US) | 2012-08-22 | — | — | EP | disclosed |
| CN-100560555-C | A kind of synthetic 1, the method for 3-two replacement-4-alkene-1-cyclo-pentanone compounds | SHANGHAI INST ORGANIC CHEM (CN) | 2009-11-18 | — | — | CN | disclosed |
| CN-101085726-A | Method for synthesizing 1,3-disubstitute-4-penten-1-one | SHANGHAI INST ORGANIC CHEM (CN) | 2007-12-12 | — | — | CN | disclosed |
| WO-2007038684-A2 | PYRROLE DERIVATIVES AS THERAPEUTIC COMPOUNDS | MYRIAD GENETICS, INC. (US) | 2007-04-05 | — | — | WO | disclosed |
| US-4446467-A | DIAZOTYPE PROCESS; PHOTOSENSITIVITY; PRINTING TICKET | DAI NIPPON PRINTING CO., LTD. (JP) | 1984-05-01 | — | — | US | disclosed |
| US-4421839-A | DIAZOTYPE PROCESS | DAI NIPPON PRINTING CO., LTD. (JP) | 1983-12-20 | — | — | US | disclosed |
| EP-0023673-A2 | Device for performing a heat-sensitive recording, heat-sensitive recording sheet, and a method for performing a heat-sensitive recording | KABUSHIKI KAISHA TOSHIBA (JP) | 1981-02-11 | — | — | EP | disclosed |