Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 3/20 | 0.68 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 5/20 | 0.57 |
| ▸ | MAOA | P21397 | 2/20 | 0.57 |
| ▸ | CMA1 | P23946 | 1/20 | 0.54 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.42 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11089929 | 0.86 | EIF2AK2 (0.63) | AHREIF2AK2MAOBMAOAPGR | |
| SCHEMBL5638486 | 0.84 | EIF2AK2 (0.61) | AHREIF2AK2MAOBPGRGAA | |
| SCHEMBL154614 | 0.81 | AHR (1.00) | AHREIF2AK2MAOBCMA1PGR | |
| SCHEMBL1900155 | 0.80 | AHR (0.77) | AHRCMA1PGRGAAPDE3B | |
| SCHEMBL11094738 | 0.80 | MAOB (0.53) | AHREIF2AK2MAOBMAOACMA1 | |
| SCHEMBL31040124 | 0.77 | PDE3B (0.66) | AHREIF2AK2MAOBMAOAGAA | |
| SCHEMBL20214 | 0.77 | PDE3B (0.66) | AHREIF2AK2MAOBMAOAGAA | |
| SCHEMBL26547713 | 0.76 | CRBN (0.61) | EIF2AK2SMN1; SMN2 | |
| SCHEMBL3484612 | 0.76 | MAOB (0.50) | AHREIF2AK2MAOBCMA1PGR | |
| SCHEMBL8584695 | 0.76 | AHR (0.86) | AHREIF2AK2MAOBCMA1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4472433-A | Phenoxyphenyl acetic acids and their medicinal use | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-09-18 | — | — | US | disclosed |
| EP-0008226-B1 | PHENYL-ALKANOIC ACID DERIVATIVES, THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-11-02 | — | — | EP | disclosed |
| EP-0008226-A2 | Phenyl-alkanoic acid derivatives, the preparation thereof and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-02-20 | — | — | EP | disclosed |