Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CDK1 | P06493 | 1/20 | 0.50 |
| ▸ | XDH | P47989 | 1/20 | 0.49 |
| ▸ | TOP1 | P11387 | 1/20 | 0.49 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11089847 | 0.93 | CDK1 (0.56) | POLBHDAC6CDK1XDHTOP1 | |
| SCHEMBL18619400 | 0.93 | HDAC6 (0.58) | HDAC6MAPK1XDHTOP1KDM4E | |
| SCHEMBL29633482 | 0.88 | HDAC6 (0.60) | POLBHDAC6XDHTOP1KDM4E | |
| SCHEMBL24440484 | 0.88 | HDAC6 (0.60) | POLBHDAC6XDHTOP1KDM4E | |
| SCHEMBL11092370 | 0.86 | HPGD (0.62) | POLBHDAC6TOP1KDM4EHPGD | |
| SCHEMBL5924535 | 0.86 | POLB (0.52) | POLBHDAC6MAPK1PDK2KDM4E | |
| SCHEMBL15985477 | 0.86 | XDH (0.51) | POLBHDAC6MAPK1XDHTOP1 | |
| SCHEMBL9725132 | 0.86 | L3MBTL1 (0.65) | ALDH1A1HSD17B10 | |
| SCHEMBL27907061 | 0.86 | L3MBTL1 (0.65) | ALDH1A1HSD17B10 | |
| SCHEMBL9142025 | 0.86 | L3MBTL1 (0.65) | ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0045523-B1 | ALPHA-SUBSTITUTED UREIDOBENZYLPENICILLANIC ACID DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | Chugai Seiyaku Kabushiki Kaisha (JP) | 1984-12-05 | — | — | EP | disclosed |
| EP-0045523-A1 | Alpha-substituted ureidobenzylpenicillanic acid derivatives and process for producing the same | Chugai Seiyaku Kabushiki Kaisha (JP) | 1982-02-10 | — | — | EP | disclosed |