Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 5/20 | 0.47 |
| ▸ | TOP1 | P11387 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TERT | O14746 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | XDH | P47989 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5924224 | 0.87 | SMN1; SMN2 (0.48) | SMN1; SMN2CA2HPGDPOLBHTT | |
| SCHEMBL11092370 | 0.84 | HPGD (0.62) | HDAC6CA2TOP1HPGDPOLB | |
| SCHEMBL11425652 | 0.83 | SMN1; SMN2 (0.65) | SMN1; SMN2HDAC6HPGDPOLBHTT | |
| SCHEMBL11092140 | 0.83 | HPGD (0.65) | SMN1; SMN2HDAC6CA2TOP1HPGD | |
| SCHEMBL11089847 | 0.81 | CDK1 (0.56) | SMN1; SMN2HDAC6TOP1HPGDPOLB | |
| SCHEMBL3543118 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2CA2HPGDPOLBHTT | |
| SCHEMBL24440484 | 0.79 | HDAC6 (0.60) | SMN1; SMN2HDAC6CA2TOP1POLB | |
| SCHEMBL29633482 | 0.79 | HDAC6 (0.60) | SMN1; SMN2HDAC6CA2TOP1POLB | |
| SCHEMBL5656002 | 0.78 | SMN1; SMN2 (0.58) | SMN1; SMN2HDAC6CA2 | |
| SCHEMBL11089138 | 0.78 | POLB (0.56) | HDAC6TOP1HPGDPOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0045523-B1 | ALPHA-SUBSTITUTED UREIDOBENZYLPENICILLANIC ACID DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | Chugai Seiyaku Kabushiki Kaisha (JP) | 1984-12-05 | — | — | EP | disclosed |
| US-4355038-A | BACTERICIDES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1982-10-19 | — | — | US | disclosed |
| EP-0045523-A1 | Alpha-substituted ureidobenzylpenicillanic acid derivatives and process for producing the same | Chugai Seiyaku Kabushiki Kaisha (JP) | 1982-02-10 | — | — | EP | disclosed |