Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | XDH | P47989 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | TOP1 | P11387 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | IARS1 | P41252 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12553807 | 0.86 | HPGD (0.60) | HPGDALDH1A1TP53MEN1KMT2A | |
| SCHEMBL10029414 | 0.83 | L3MBTL1 (0.58) | HPGDALDH1A1CA2XDHCA12 | |
| SCHEMBL11089200 | 0.83 | SMN1; SMN2 (0.51) | HPGDCA2XDHCA12CA1 | |
| SCHEMBL24440484 | 0.82 | HDAC6 (0.60) | ALDH1A1CA2XDHCA12CA1 | |
| SCHEMBL29633482 | 0.82 | HDAC6 (0.60) | ALDH1A1CA2XDHCA12CA1 | |
| SCHEMBL15985474 | 0.81 | HDAC6 (0.55) | HPGDALDH1A1TP53CA2XDH | |
| SCHEMBL4506194 | 0.81 | ALDH1A1 (0.68) | HPGDALDH1A1TP53CA2CA12 | |
| SCHEMBL11092370 | 0.81 | HPGD (0.62) | HPGDALDH1A1CA2CA12CA1 | |
| SCHEMBL18619400 | 0.81 | HDAC6 (0.58) | XDHHDAC6TOP1SMN1; SMN2 | |
| SCHEMBL11094551 | 0.80 | ALDH1A1 (0.54) | HPGDALDH1A1CA2XDHCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0045523-B1 | ALPHA-SUBSTITUTED UREIDOBENZYLPENICILLANIC ACID DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | Chugai Seiyaku Kabushiki Kaisha (JP) | 1984-12-05 | — | — | EP | disclosed |
| US-4355038-A | BACTERICIDES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1982-10-19 | — | — | US | disclosed |
| EP-0045523-A1 | Alpha-substituted ureidobenzylpenicillanic acid derivatives and process for producing the same | Chugai Seiyaku Kabushiki Kaisha (JP) | 1982-02-10 | — | — | EP | disclosed |