Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | ACACA | Q13085 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11089401 | 1.00 | ALDH1A1 (0.39) | ALDH1A1ACLYTSHRACACBACACA | |
| SCHEMBL10837387 | 0.82 | ALDH1A1 (0.39) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL10837394 | 0.82 | ALDH1A1 (0.39) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL10837392 | 0.82 | ALDH1A1 (0.39) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL1114811 | 0.81 | MAPK1 (0.40) | ALDH1A1ACLYTSHRACACBACACA | |
| SCHEMBL13083872 | 0.77 | ACLY (0.36) | ALDH1A1ACLYTSHRACACBACACA | |
| SCHEMBL23217911 | 0.72 | ACLY (0.48) | ALDH1A1ACLYTSHRACACBACACA | |
| SCHEMBL18574652 | 0.72 | — | — | |
| SCHEMBL23217912 | 0.72 | ACLY (0.48) | ALDH1A1ACLYTSHRACACBACACA | |
| SCHEMBL1360886 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4489092-A | Prostanoic acid derivatives and their preparation | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-12-18 | — | — | US | disclosed |
| US-4359467-A | Prostanoic acid derivatives and their preparation | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-11-16 | — | — | US | disclosed |
| US-4284646-A | Prostanoic acid derivatives and their preparation | SCHERING AKTIENGESELLSCHAFT (DE) | 1981-08-18 | — | — | US | disclosed |