Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 7/20 | 0.41 |
| ▸ | CA2 | P00918 | 7/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11089460 | 1.00 | ACE (0.45) | ACEKMT2ACA1CA2 | |
| SCHEMBL11084537 | 0.85 | CA2 (0.44) | ACEKMT2ACA1CA2 | |
| SCHEMBL11084531 | 0.85 | CA2 (0.44) | ACEKMT2ACA1CA2 | |
| SCHEMBL11088267 | 0.82 | CA1 (0.41) | CA1CA2 | |
| SCHEMBL11309596 | 0.80 | CA1 (0.40) | ACEKMT2ACA1CA2 | |
| SCHEMBL11309604 | 0.80 | CA1 (0.40) | ACEKMT2ACA1CA2 | |
| SCHEMBL11309600 | 0.80 | CA1 (0.40) | ACEKMT2ACA1CA2 | |
| SCHEMBL11561580 | 0.79 | ACE (0.62) | ACEKMT2A | |
| SCHEMBL10997789 | 0.79 | ACE (0.62) | ACEKMT2A | |
| SCHEMBL11079988 | 0.79 | CA1 (0.57) | CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4450275-A | HYPOTENSIVE AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1984-05-22 | — | — | US | claimed |
| JP-58113183-A | — | — | None | — | — | JP | disclosed |
| JP-55049352-A | — | — | None | — | — | JP | disclosed |
| US-4450275-A | HYPOTENSIVE AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1984-05-22 | — | — | US | disclosed |
| JP-S58113183-A | CYCLIC IMINOCARBOXYLIC ACID DERIVATIVE AND ITS SALT | YOSHITOMI PHARMACEUT IND LTD | 1983-07-05 | — | — | JP | disclosed |
| JP-S5549352-A | CYCLIC IMINOCARBOXYLIC ACID DERIVATIVE AND ITS SALT | YOSHITOMI PHARMACEUT IND LTD | 1980-04-09 | — | — | JP | disclosed |