Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | ACE | P12821 | 7/20 | 0.43 |
| ▸ | REN | P00797 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | PEPD | P12955 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11084531 | 1.00 | CA2 (0.44) | CA2ACERENKDM4ELMNA | |
| SCHEMBL11085165 | 0.87 | WNT3 (0.43) | CA2ACERENKDM4ELMNA | |
| SCHEMBL11085170 | 0.87 | WNT3 (0.43) | CA2ACERENKDM4ELMNA | |
| SCHEMBL11089460 | 0.85 | ACE (0.45) | CA2ACEKMT2ACA1 | |
| SCHEMBL11090985 | 0.85 | ACE (0.43) | CA2ACERENKDM4ELMNA | |
| SCHEMBL11090981 | 0.85 | ACE (0.43) | CA2ACERENKDM4ELMNA | |
| SCHEMBL11089449 | 0.85 | ACE (0.45) | CA2ACEKMT2ACA1 | |
| SCHEMBL11086491 | 0.84 | CA2 (0.44) | CA2ACERENKDM4ELMNA | |
| SCHEMBL11086488 | 0.84 | CA2 (0.44) | CA2ACERENKDM4ELMNA | |
| SCHEMBL11084329 | 0.82 | CA2 (0.47) | CA2ACEKDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4450275-A | HYPOTENSIVE AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1984-05-22 | — | — | US | claimed |
| JP-56083419-A | — | — | None | — | — | JP | disclosed |
| US-4450275-A | HYPOTENSIVE AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1984-05-22 | — | — | US | disclosed |
| JP-S5683419-A | REMEDY FOR HYPERTENSION | YOSHITOMI PHARMACEUT IND LTD | 1981-07-08 | — | — | JP | disclosed |