Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.47 |
| ▸ | QPCT | Q16769 | 2/20 | 0.47 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | PRKCI | P41743 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9224384 | 0.98 | EPHX1 (0.51) | DRD2EPHX1S1PR4S1PR1S1PR5 | |
| SCHEMBL8656478 | 0.95 | DRD2 (0.52) | DRD2EPHX1QPCTMMP12PRKCI | |
| SCHEMBL9222951 | 0.88 | QPCT (0.50) | DRD2EPHX1QPCTMMP12PRKCI | |
| SCHEMBL11088260 | 0.87 | HTR1A (0.46) | DRD2EPHX1S1PR4S1PR1S1PR5 | |
| SCHEMBL9224383 | 0.86 | HTR1A (0.48) | EPHX1S1PR4S1PR1S1PR5QPCT | |
| SCHEMBL28872961 | 0.83 | QPCTL (0.51) | QPCT | |
| SCHEMBL27333684 | 0.83 | DRD2 (0.50) | DRD2QPCTMMP12PRKCIKDM4E | |
| SCHEMBL3796388 | 0.82 | DRD2 (0.52) | DRD2QPCTMMP12PRKCIKDM4E | |
| SCHEMBL17267044 | 0.82 | DRD2 (0.52) | DRD2QPCTMMP12PRKCIKDM4E | |
| SCHEMBL8656473 | 0.82 | POLA1 (0.46) | DRD2EPHX1QPCTMAPTHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4438135-A | ANTHELMINTICS; NEMATOCIDES; PARASITICIDES; VETERINARY MEDICINE | SMITHKLINE BECKMAN CORPORATION (US) | 1984-03-20 | — | — | US | disclosed |