Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | EDNRA | P25101 | 1/20 | 0.48 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.42 |
| ▸ | MATK | P42679 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11271171 | 0.92 | MEN1 (0.52) | KDM4EMEN1KMT2AHSD17B10CYP2C9 | |
| SCHEMBL11006549 | 0.85 | KMT2A (0.51) | KDM4EMEN1KMT2AHSD17B10CYP2C9 | |
| SCHEMBL11282959 | 0.85 | MEN1 (0.50) | KDM4EMEN1KMT2AHSD17B10CYP2C9 | |
| SCHEMBL11278689 | 0.84 | LMNA (0.48) | KDM4EMEN1KMT2AHSD17B10CYP2C9 | |
| SCHEMBL2097125 | 0.83 | LMNA (0.48) | KDM4EMEN1KMT2AHSD17B10CYP2C9 | |
| SCHEMBL2094951 | 0.83 | LMNA (0.48) | KDM4EMEN1KMT2AHSD17B10CYP2C9 | |
| SCHEMBL11500738 | 0.82 | HTT (0.40) | KDM4EMEN1KMT2AHSD17B10POLB | |
| SCHEMBL9535386 | 0.81 | LMNA (0.60) | KDM4EMEN1KMT2AHSD17B10CYP2C9 | |
| SCHEMBL11270051 | 0.81 | MEN1 (0.53) | KDM4EMEN1KMT2AHSD17B10CYP2C9 | |
| SCHEMBL11334146 | 0.80 | MEN1 (0.52) | KDM4EMEN1KMT2AHSD17B10CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4442101-A | TREATMENT OF BACTERIAL DISEASES | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1984-04-10 | — | — | US | disclosed |
| US-4359578-A | Naphthyridine derivatives and salts thereof useful as antibacterial agents | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1982-11-16 | — | — | US | disclosed |
| US-4352803-A | BACTERICIDES | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1982-10-05 | — | — | US | disclosed |