Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11090022 | 0.88 | MAPT (0.47) | MAPTLMNATSHRNPSR1TP53 | |
| SCHEMBL11087146 | 0.83 | MAPT (0.60) | MAPTLMNATSHRNPSR1TP53 | |
| SCHEMBL11089591 | 0.82 | MAPT (0.47) | MAPTLMNATSHRNPSR1GAA | |
| SCHEMBL11091891 | 0.82 | LMNA (0.55) | MAPTLMNATSHRTP53MAPK10 | |
| SCHEMBL11084694 | 0.79 | TP53 (0.51) | MAPTLMNATSHRNPSR1TP53 | |
| SCHEMBL11090510 | 0.79 | PDGFRB (0.55) | MAPTLMNATSHRNPSR1TP53 | |
| SCHEMBL11091998 | 0.77 | LMNA (0.49) | MAPTLMNATSHRNPSR1TP53 | |
| SCHEMBL11087676 | 0.77 | MAPT (0.59) | MAPTLMNATSHRTP53MAPK10 | |
| SCHEMBL11130485 | 0.77 | KDM4E (0.47) | MAPTLMNATSHRNPSR1TP53 | |
| SCHEMBL11091553 | 0.76 | MAPT (0.49) | MAPTLMNANPSR1TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460773-A | ANTITUMOR AGENTS, VIRICIDES | LION CORPORATION (JP) | 1984-07-17 | — | — | US | disclosed |