Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23867565 | 0.88 | CYP1A2 (0.57) | KMT2AHPGDSMN1; SMN2CYP1A2MEN1 | |
| SCHEMBL7257708 | 0.83 | KMT2A (0.44) | KMT2AHPGDSMN1; SMN2CYP1A2MEN1 | |
| SCHEMBL29488190 | 0.80 | KMT2A (0.44) | KMT2AHPGDSMN1; SMN2CYP1A2MEN1 | |
| SCHEMBL9485267 | 0.78 | LMNA (0.64) | KMT2AHPGDSMN1; SMN2CYP1A2MEN1 | |
| SCHEMBL8502483 | 0.78 | MAPT (0.45) | KMT2AHPGDSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL9391341 | 0.76 | CYP1A2 (0.46) | KMT2AHPGDSMN1; SMN2CYP1A2MEN1 | |
| SCHEMBL7258031 | 0.75 | LMNA (0.69) | KMT2AHPGDSMN1; SMN2CYP1A2MEN1 | |
| SCHEMBL2194514 | 0.74 | CYP1A2 (0.48) | KMT2AHPGDSMN1; SMN2CYP1A2MEN1 | |
| SCHEMBL26039239 | 0.74 | ALDH1A1 (0.41) | KMT2AHPGDSMN1; SMN2MEN1ALDH1A1 | |
| Albendazole SCHEMBL7969988 | 0.74 | LMNA (0.83) | KMT2AHPGDSMN1; SMN2CYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153385-B2 | Target protein and target gene in drug designing and screening method | REVERSE PROTEOMICS RESEARCH INSTITUTE CO., LTD. (JP) | 2012-04-10 | — | — | US | disclosed |
| US-8153385-B2 | Target protein and target gene in drug designing and screening method | REVERSE PROTEOMICS RESEARCH INSTITUTE CO., LTD. (JP) | 2012-04-10 | — | — | US | disclosed |
| US-20100136524-A1 | TARGET PROTEIN AND TARGET GENE IN DRUG DESIGNING AND SCREENING METHOD | REVERSE PROTEOMICS RESEARCH INSTITUTE CO., LTD. (JP) | 2010-06-03 | — | — | US | disclosed |
| US-20100136524-A1 | TARGET PROTEIN AND TARGET GENE IN DRUG DESIGNING AND SCREENING METHOD | REVERSE PROTEOMICS RESEARCH INSTITUTE CO., LTD. (JP) | 2010-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100136524-A1 | TARGET PROTEIN AND TARGET GENE IN DRUG DESIGNING AND SCREENING METHOD | CHP1, CMA1, CARHSP1 | KMT2A 3893/4885HPGD 2335/4885SMN1; SMN2 4516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.