Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11092108 | 0.92 | HSD17B3 (0.46) | KMT2AALDH1A1MAPTHPGDPOLB | |
| SCHEMBL11401302 | 0.91 | KMT2A (0.47) | KMT2AALDH1A1MAPTHPGDPOLB | |
| SCHEMBL11091798 | 0.91 | ALDH1A1 (0.46) | KMT2AALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL11394852 | 0.90 | HDAC1 (0.45) | KMT2AALDH1A1MAPTHPGDPOLB | |
| SCHEMBL11088734 | 0.89 | KMT2A (0.42) | KMT2AALDH1A1MAPTHPGDPOLB | |
| SCHEMBL11131374 | 0.87 | MAPT (0.47) | KMT2AALDH1A1MAPTHPGDPOLB | |
| SCHEMBL11092734 | 0.84 | KMT2A (0.44) | KMT2AALDH1A1MAPTHPGDPOLB | |
| SCHEMBL11090169 | 0.84 | EGFR (0.48) | ALDH1A1MAPTL3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL11609561 | 0.84 | KMT2A (0.57) | KMT2AALDH1A1MAPTPOLBTDP1 | |
| SCHEMBL11095919 | 0.83 | KMT2A (0.44) | KMT2AALDH1A1POLBL3MBTL1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4486443-A | PROSTAGLANDIN-LIKE EFFECTS | BURROUGHS WELLCOME CO. (US) | 1984-12-04 | — | — | US | disclosed |
| US-4262128-A | HAVING PROSTAGLANDIN-LIKE BIOLOGICAL PROPERTIES | BURROUGHS WELLCOME CO. (US) | 1981-04-14 | — | — | US | disclosed |