Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CCKBR | P32239 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11089622 | 0.91 | KMT2A (0.45) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL11092108 | 0.90 | HSD17B3 (0.46) | KMT2AALDH1A1MAPTHPGDL3MBTL1 | |
| SCHEMBL11091798 | 0.89 | ALDH1A1 (0.46) | KMT2AMEN1LMNAALDH1A1MAPT | |
| SCHEMBL11394852 | 0.88 | HDAC1 (0.45) | KMT2AMEN1LMNAALDH1A1MAPT | |
| SCHEMBL11088734 | 0.87 | KMT2A (0.42) | KMT2ALMNAALDH1A1MAPTHPGD | |
| SCHEMBL11131374 | 0.85 | MAPT (0.47) | KMT2ALMNAALDH1A1MAPTHPGD | |
| SCHEMBL11090280 | 0.83 | KMT2A (0.43) | KMT2AALDH1A1L3MBTL1CCKBRPOLB | |
| SCHEMBL11092734 | 0.83 | KMT2A (0.44) | KMT2AALDH1A1MAPTHPGDL3MBTL1 | |
| SCHEMBL11090169 | 0.82 | EGFR (0.48) | LMNAALDH1A1MAPTL3MBTL1MAPK1 | |
| SCHEMBL7460876 | 0.82 | KMT2A (0.53) | KMT2AMEN1LMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4262128-A | HAVING PROSTAGLANDIN-LIKE BIOLOGICAL PROPERTIES | BURROUGHS WELLCOME CO. (US) | 1981-04-14 | — | — | US | disclosed |