SCHEMBL11089650

SCHEMBL11089650

CC(O)(CCO)C1CCCCC1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 4/20 0.33
CHRM2 P08172 3/20 0.33
CHRM1 P11229 3/20 0.33
KCNH2 Q12809 3/20 0.33
SSTR4 P31391 1/20 0.33
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
ALOX12 P18054 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
CHRM3 P20309 2/20 0.30
GRIN2D O15399 1/20 0.30
GRIN3B O60391 1/20 0.30
HRH1 P35367 1/20 0.30
GRIN1 Q05586 1/20 0.30
GRIN2A Q12879 1/20 0.30
GRIN2B Q13224 1/20 0.30
GRIN2C Q14957 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11981967 0.82 CYP1A2 (0.38) CYP2D6CHRM2CHRM1KCNH2SSTR4
SCHEMBL28578100 0.82 CYP1A2 (0.38) CYP2D6CHRM2CHRM1KCNH2SSTR4
SCHEMBL11139674 0.80 SSTR4 (0.39) CYP2D6CHRM2CHRM1KCNH2SSTR4
SCHEMBL11094087 0.80 CHRM2 (0.32) CYP2D6CHRM2CHRM1KCNH2SSTR4
SCHEMBL2777672 0.79 MEN1 (0.40) CYP2D6CHRM2CHRM1KCNH2SSTR4
SCHEMBL6866115 0.78 CYP1A2 (0.45) CYP2D6CHRM2CHRM1KCNH2SIGMAR1
SCHEMBL29222449 0.77 L3MBTL1 (0.37) CYP2D6CHRM2CHRM1KCNH2SSTR4
SCHEMBL10876420 0.76 CYP1A2 (0.36) CYP2D6CHRM2CHRM1KCNH2SSTR4
SCHEMBL10876431 0.76 CYP1A2 (0.36) CYP2D6CHRM2CHRM1KCNH2SSTR4
SCHEMBL10946626 0.76 CYP2D6 (0.32) CYP2D6CHRM2CHRM1KCNH2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4460595-A Using urazole analogs of prostaglandins for bronchodilation BEECHAM GROUP LIMITED (GB) 1984-07-17 US disclosed
US-4367338-A BRONCHODILATORS, ANTICOAGULANTS BEECHAM GROUP LIMITED (GB) 1983-01-04 US disclosed