Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2151436 | 0.87 | — | — | |
| SCHEMBL25418137 | 0.81 | MEN1 (0.36) | MEN1ALDH1A1LMNAALOX12KMT2A | |
| SCHEMBL4681944 | 0.80 | SMN1; SMN2 (0.42) | MEN1ALDH1A1LMNAALOX12KMT2A | |
| SCHEMBL18792667 | 0.80 | MEN1 (0.34) | MEN1ALDH1A1LMNAALOX12KMT2A | |
| SCHEMBL11089650 | 0.79 | CYP2D6 (0.33) | MEN1ALDH1A1LMNAALOX12KMT2A | |
| SCHEMBL10387752 | 0.78 | CYP1A2 (0.41) | MEN1ALDH1A1LMNAALOX12KMT2A | |
| SCHEMBL7526068 | 0.78 | CYP1A2 (0.41) | MEN1ALDH1A1LMNAALOX12KMT2A | |
| SCHEMBL345668 | 0.77 | SMN1; SMN2 (0.39) | MEN1ALDH1A1LMNAALOX12KMT2A | |
| SCHEMBL6491689 | 0.76 | MEN1 (0.36) | MEN1ALDH1A1LMNAALOX12KMT2A | |
| SCHEMBL1930395 | 0.76 | CYP1A2 (0.44) | MEN1ALDH1A1LMNAALOX12KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2157968-A1 | BENEFIT AGENT CONTAINING DELIVERY PARTICLE | APPLETON PAPERS INC. (US) | 2010-03-03 | — | — | EP | claimed |
| WO-2008153882-A1 | BENEFIT AGENT CONTAINING DELIVERY PARTICLE | APPLETON PAPERS INC. (US) | 2008-12-18 | — | — | WO | claimed |
| US-6958402-B2 | 3-(imidazolyl)-2-alkoxypropanoic acids | PFIZER, INC. (US) | 2005-10-25 | — | — | US | disclosed |
| US-20040254164-A1 | 3-(imidazolyl)-2-alkoxypropanoic acids | PFIZER INC. (US) | 2004-12-16 | — | — | US | disclosed |
| EP-1467731-A1 | 3-(IMIDAZOLYL)-2-ALKOXYPROPANOIC ACIDS AS TAFIA INHIBITORS | Pfizer Limited (GB) | 2004-10-20 | — | — | EP | disclosed |
| US-6713496-B2 | 3-(imidazolyl)-2-alkoxypropanoic acids | PFIZER INC | 2004-03-30 | — | — | US | disclosed |
| US-20030199522-A1 | 3-(Imidazolyl)-2-alkoxypropanoic acids | PFIZER INC. | 2003-10-23 | — | — | US | disclosed |
| WO-2003061652-A1 | 3-(IMIDAZOLYL)-2-ALKOXYPROPANOIC ACIDS AS TAFIA INHIBITORS | PFIZER LIMITED (GB) | 2003-07-31 | — | — | WO | disclosed |
| WO-2003061652-A1 | 3-(IMIDAZOLYL)-2-ALKOXYPROPANOIC ACIDS AS TAFIA INHIBITORS | PFIZER LIMITED (GB) | 2003-07-31 | — | — | WO | disclosed |
| US-5104503-A | Radiation in presence of group 2b metal | YALE UNIVERSITY (US) | 1992-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030199522-A1 | 3-(Imidazolyl)-2-alkoxypropanoic acids | F2, FGB, F7 | MEN1 1716/4885ALDH1A1 191/4885LMNA 1149/4885 |
| US-20040254164-A1 | 3-(imidazolyl)-2-alkoxypropanoic acids | F2, FGB, F7 | MEN1 1756/4885ALDH1A1 217/4885LMNA 1239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.