Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.40 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.40 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11090774 | 0.89 | GAA (0.49) | TSHRGAACDK1SMN1; SMN2KCNJ6 | |
| SCHEMBL11086619 | 0.89 | GAA (0.51) | TSHRGAACDK1SMN1; SMN2 | |
| SCHEMBL10454399 | 0.88 | TSHR (0.54) | TSHRGAACDK1SMN1; SMN2LMNA | |
| SCHEMBL11085204 | 0.85 | CDK1 (0.41) | TSHRGAACDK1SMN1; SMN2KCNJ6 | |
| SCHEMBL10508252 | 0.82 | GAA (0.58) | GAACDK1KMT2A | |
| SCHEMBL11161956 | 0.82 | TSHR (0.61) | TSHRGAACDK1SMN1; SMN2 | |
| SCHEMBL10839228 | 0.82 | SMN1; SMN2 (0.47) | TSHRGAACDK1SMN1; SMN2 | |
| SCHEMBL11088741 | 0.81 | GAA (0.49) | TSHRGAACDK1SMN1; SMN2 | |
| SCHEMBL9730627 | 0.81 | GAA (0.59) | TSHRGAACDK1 | |
| SCHEMBL11068347 | 0.81 | GAA (0.48) | TSHRGAACDK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0023141-B1 | HERBICIDAL SULFONAMIDES, PREPARATION AND USE THEREOF, COMPOSITIONS CONTAINING THEM, INTERMEDIATES THEREFOR AND PREPARATION OF SUCH INTERMEDIATES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-04-11 | — | — | EP | claimed |
| EP-0023141-A2 | Herbicidal sulfonamides, preparation and use thereof, compositions containing them, intermediates therefor and preparation of such intermediates | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-01-28 | — | — | EP | claimed |
| EP-0023141-A2 | Herbicidal sulfonamides, preparation and use thereof, compositions containing them, intermediates therefor and preparation of such intermediates | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-01-28 | — | — | EP | disclosed |