Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TERT | O14746 | 6/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19101387 | 0.92 | PRMT1 (0.37) | PRMT1MEN1KMT2AALDH1A1USP2 | |
| SCHEMBL21846601 | 0.86 | PRMT1 (0.33) | PRMT1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL21892022 | 0.84 | PRMT1 (0.34) | PRMT1MEN1KMT2AALDH1A1USP2 | |
| SCHEMBL19101539 | 0.83 | PRMT1 (0.56) | PRMT1MEN1KMT2AALDH1A1USP2 | |
| SCHEMBL21846596 | 0.82 | PRMT1 (0.40) | PRMT1MEN1KMT2AALDH1A1USP2 | |
| SCHEMBL19101428 | 0.76 | PRMT1 (0.49) | PRMT1MEN1KMT2AALDH1A1USP2 | |
| SCHEMBL12170761 | 0.75 | TERT (0.56) | PRMT1MEN1KMT2AALDH1A1USP2 | |
| SCHEMBL29355182 | 0.75 | TERT (0.56) | PRMT1MEN1KMT2AALDH1A1USP2 | |
| SCHEMBL9968962 | 0.75 | TERT (0.56) | PRMT1MEN1KMT2AALDH1A1USP2 | |
| SCHEMBL710594 | 0.75 | TERT (0.56) | PRMT1MEN1KMT2AALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3623451-B1 | COMPOUND | MERCK PATENT GMBH (DE) | 2021-01-20 | — | — | EP | disclosed |