Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1660471 | 0.85 | TDP1 (0.44) | ALDH1A1POLBSRD5A2TDP1ELANE | |
| SCHEMBL10707615 | 0.82 | SMN1; SMN2 (0.40) | ALDH1A1HTTKMT2APOLBSMN1; SMN2 | |
| SCHEMBL195744 | 0.81 | KDM4E (0.40) | ALDH1A1POLBSMN1; SMN2HSD17B10MAPT | |
| SCHEMBL28668452 | 0.77 | ALDH1A1 (0.49) | ALDH1A1HTTMAPK14MAPK13MAPK12 | |
| SCHEMBL30692364 | 0.77 | ALDH1A1 (0.49) | ALDH1A1HTTMAPK14MAPK13MAPK12 | |
| SCHEMBL14976 | 0.76 | MAPT (0.44) | ALDH1A1POLBNPC1MAPTTDP1 | |
| SCHEMBL29448528 | 0.76 | MAPT (0.44) | ALDH1A1POLBNPC1MAPTTDP1 | |
| SCHEMBL2081884 | 0.75 | ALDH1A1 (0.39) | ALDH1A1KMT2APOLBNPC1RAB9A | |
| Hydrogen Peroxide SCHEMBL8974942 | 0.74 | TDP1 (0.46) | ALDH1A1POLBNPC1HSD17B10MAPT | |
| SCHEMBL30949796 | 0.74 | MAPT (0.43) | ALDH1A1POLBNPC1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0125140-A2 | Improvements in or relating to radiation sensitive plates | VICKERS PLC (GB) | 1984-11-14 | — | — | EP | disclosed |