SCHEMBL195744

SCHEMBL195744

CC(C)(C)c1cc(C(=O)OO)ccc1C(=O)OO

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.40
MAPT P10636 2/20 0.39
ATM Q13315 2/20 0.39
HSD17B10 Q99714 2/20 0.39
ALDH1A1 P00352 2/20 0.39
GAA P10253 2/20 0.39
GLA P06280 1/20 0.39
HPGD P15428 1/20 0.39
CASP1 P29466 1/20 0.39
CASP7 P55210 1/20 0.39
TDP1 Q9NUW8 2/20 0.38
HSP90AA1 P07900 2/20 0.37
HSP90AB1 P08238 2/20 0.37
NR1H4 Q96RI1 2/20 0.37
ESRRA P11474 1/20 0.36
POLB P06746 1/20 0.35
NOTUM Q6P988 1/20 0.35
ALOX5 P09917 1/20 0.35
PTGS1 P23219 1/20 0.35
PTGS2 P35354 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL195743 0.91 TDP1 (0.44) KDM4EMAPTATMHSD17B10ALDH1A1
SCHEMBL1660471 0.84 TDP1 (0.44) KDM4EATMALDH1A1HPGDTDP1
SCHEMBL11030946 0.83 THRA (0.44) MAPTALDH1A1GAAHPGDHSP90AA1
SCHEMBL2081884 0.82 ALDH1A1 (0.39) MAPTALDH1A1HPGDNR1H4POLB
SCHEMBL28918215 0.82 KDM4E (0.59) KDM4EMAPTATMHSD17B10ALDH1A1
SCHEMBL10707615 0.82 SMN1; SMN2 (0.40) KDM4EMAPTALDH1A1GAAHPGD
SCHEMBL11089693 0.81 ALDH1A1 (0.46) MAPTHSD17B10ALDH1A1TDP1POLB
SCHEMBL11422801 0.81 NR1H4 (0.49) KDM4EMAPTALDH1A1GAACASP1
SCHEMBL2080413 0.79 NPC1 (0.46) MAPTALDH1A1GAAHPGDNR1H4
SCHEMBL1348417 0.77 POLB (0.35) MAPTATMTDP1HSP90AA1HSP90AB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11186663-B2 High filler loaded compositions with high melt flow polyolefins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-11-30 US claimed
JP-2012500327-A 2012-01-05 JP claimed
EP-2315796-A1 CROSSLINKED POLYMER COMPOSITION Nova Chemicals Inc. (US) 2011-05-04 EP claimed
WO-2010022208-A1 CROSSLINKED POLYMER COMPOSITION NOVA CHEMICALS INC. (US) 2010-02-25 WO claimed
US-20100048752-A1 CROSSLINKED POLYMER COMPOSITION NOVA CHEMICALS INC. (US) 2010-02-25 US claimed
US-6376585-B1 BINDER MIXTURE OF CARBONATE, ETHYLENEBISAMIDE WAX AND WETTING AGENT APEX ADVANCED TECHNOLOGIES, LLC 2002-04-23 US claimed
US-11976188-B2 Polymer compositions with high color pigments loading ExxonMobil Engineering & Technology Company (US) 2024-05-07 US disclosed
US-11186663-B2 High filler loaded compositions with high melt flow polyolefins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-11-30 US disclosed
US-20200181380-A1 Polymer Compositions with High Color Pigments Loading EXXONMOBIL CHEMICAL PATENTS INC (US) 2020-06-11 US disclosed
US-20180105624-A1 High Filler Loaded Compositions with High Melt Flow Polyolefins EXXONMOBIL CHEMICAL PATENTS INC. 2018-04-19 US disclosed
US-9464181-B2 High filler loaded polymer composition EXXONMOBIL CHEMICAL PATENTS INC. (US) 2016-10-11 US disclosed
EP-2643409-B1 HIGH FILLER LOADED POLYMER COMPOSITION EXXONMOBIL CHEM PATENTS INC (US) 2016-06-08 EP disclosed
US-20150038637-A1 High Filler Loaded Polymer Composition ExxonMobil Asia Pacific Research & Development Co., Ltd (US) 2015-02-05 US disclosed
US-5876813-A Laminated foam structures with enhanced properties SENITNEL PRODUCTS CORP (US) 1999-03-02 US disclosed
US-5859076-A CROSSLINKING; EXPANSION; EXTRUSION; COMPRESSION MOLDING; GOOD CUSHIONING PROPERTIES AND NON-ALLERGENIC SENTINEL PRODUCTS CORP. (US) 1999-01-12 US disclosed
US-5844009-A Cross-linked low-density polymer foam SENTINEL PRODUCTS CORP. (US) 1998-12-01 US disclosed
WO-1998001294-A1 LAMINATED FOAM STRUCTURES WITH ENHANCED PROPERTIES SENTINEL PRODUCTS CORP. (US) 1998-01-15 WO disclosed
WO-1997048538-A1 POLYMER BLEND SENTINEL PRODUCTS CORP. (US) 1997-12-24 WO disclosed
EP-0803530-A2 Cross-linked polyolefin tape Sentinel Products Corp. (US) 1997-10-29 EP disclosed
EP-0702032-A2 Cross-linked foam structures of essentially linear polyolefines and process for manufacture Sentinel Products Corp. (US) 1996-03-20 EP disclosed