Thiosulfuric Acid

Thiosulfuric Acid

SCHEMBL11089902

CNC(=O)c1ccccc1.O=S(O)(O)=S

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.52
HDAC8 Q9BY41 3/20 0.50
HDAC6 Q9UBN7 3/20 0.50
HDAC2 Q92769 2/20 0.50
ALDH1A1 P00352 2/20 0.50
HDAC3 O15379 1/20 0.48
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
IDO1 P14902 1/20 0.48
ALOX15 P16050 1/20 0.48
HDAC1 Q13547 1/20 0.48
CA9 Q16790 1/20 0.48
HDAC7 Q8WUI4 1/20 0.48
HSD17B10 Q99714 1/20 0.48
NCOR2 Q9Y618 1/20 0.48
EPHX1 P07099 2/20 0.47
GAA P10253 2/20 0.47
KDM4E B2RXH2 1/20 0.47
HPGD P15428 1/20 0.47
TSHR P16473 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiosulfuric Acid SCHEMBL11089898 0.88 CA2 (0.52) CA2HDAC8HDAC6HDAC2ALDH1A1
SCHEMBL6100 0.87 HDAC8 (0.62) CA2HDAC8HDAC6HDAC2ALDH1A1
SCHEMBL26124213 0.86 CA2 (0.53) CA2HDAC8HDAC6HDAC2ALDH1A1
Hydrochloric Acid SCHEMBL5866386 0.85 HDAC8 (0.60) CA2HDAC8HDAC6HDAC2ALDH1A1
SCHEMBL7796539 0.85 HDAC8 (0.60) CA2HDAC8HDAC6HDAC2ALDH1A1
Hydrochloric Acid SCHEMBL2915137 0.85 HDAC8 (0.60) CA2HDAC8HDAC6HDAC2ALDH1A1
Dimethylamine SCHEMBL10918737 0.85 HDAC8 (0.60) CA2HDAC8HDAC6HDAC2ALDH1A1
Methane SCHEMBL15893673 0.85 HDAC8 (0.67) CA2HDAC8HDAC6HDAC2ALDH1A1
SCHEMBL11130438 0.85 HDAC8 (0.60) CA2HDAC8HDAC6HDAC2ALDH1A1
Hydrochloric Acid SCHEMBL5075431 0.85 HDAC8 (0.60) CA2HDAC8HDAC6HDAC2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0018100-B1 SUBSTITUTED AROMATIC BIOLOGICALLY ACTIVE COMPOUND, A PROCESS FOR ITS PREPARATION AND ITS USE AS BIOCIDE IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-01-18 EP disclosed