Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | PPIA | P62937 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11085109 | 0.87 | TP53 (0.44) | KMT2AMEN1ALDH1A1MAPTALOX15 | |
| SCHEMBL11076174 | 0.82 | CYP2C8 (0.50) | KMT2AMEN1ALDH1A1RAB9ASMN1; SMN2 | |
| Maleic Acid SCHEMBL11085674 | 0.78 | SLC6A2 (0.41) | L3MBTL1 | |
| Fumaric Acid SCHEMBL11085704 | 0.78 | SLC6A2 (0.41) | L3MBTL1 | |
| SCHEMBL11090007 | 0.77 | ERN1 (0.44) | L3MBTL1KCNMA1CHRM2CHRM4CHRM5 | |
| SCHEMBL4441884 | 0.77 | RECQL (0.49) | L3MBTL1KMT2ARECQLMEN1ALDH1A1 | |
| SCHEMBL611188 | 0.75 | RECQL (0.58) | L3MBTL1KMT2AKCNMA1RECQLPPIA | |
| SCHEMBL11646628 | 0.74 | KCNMA1 (0.60) | KMT2AKCNMA1RECQLMEN1ALDH1A1 | |
| SCHEMBL333224 | 0.74 | RECQL (0.71) | L3MBTL1KMT2AKCNMA1RECQLPPIA | |
| SCHEMBL29515875 | 0.74 | RECQL (0.71) | L3MBTL1KMT2AKCNMA1RECQLPPIA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4434100-A | TRANQUILIZING, ANTICONVULSANTS, ANXIOLYTIC | CIBA-GEIGY CORPORATION (US) | 1984-02-28 | — | — | US | disclosed |
| US-4356176-A | TRANQUILIZERS, ANTICONVULSANT | CIBA-GEIGY CORPORATION (US) | 1982-10-26 | — | — | US | disclosed |
| US-4315926-A | ANXIOLYTIC AGENTS | CIBA-GEIGY CORPORATION (US) | 1982-02-16 | — | — | US | disclosed |