Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C8 | P10632 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11089928 | 0.82 | L3MBTL1 (0.43) | ALDH1A1TP53MAPTSMN1; SMN2POLB | |
| SCHEMBL11082147 | 0.78 | CYP2C8 (0.54) | CYP2C8CYP2C9ALDH1A1HTTNPSR1 | |
| SCHEMBL28157462 | 0.74 | NR4A1 (0.61) | CYP2C8CYP2C9ALDH1A1HTTNPSR1 | |
| SCHEMBL3093625 | 0.74 | AKR1C3 (0.55) | ALDH1A1NPSR1HSP90AA1ATMTLR9 | |
| SCHEMBL4020068 | 0.74 | ALDH1A1 (0.47) | ALDH1A1HTTNPSR1MITFHSP90AA1 | |
| SCHEMBL27513043 | 0.74 | GABRP (0.55) | ALDH1A1HTTNPSR1MITFHSP90AA1 | |
| SCHEMBL12603660 | 0.74 | MAPT (0.58) | CYP2C8CYP2C9ALDH1A1HTTNPSR1 | |
| SCHEMBL4441884 | 0.74 | RECQL (0.49) | ALDH1A1HTTNPSR1ATMTP53 | |
| SCHEMBL2875670 | 0.73 | TP53 (0.65) | CYP2C9ALDH1A1HTTNPSR1MITF | |
| SCHEMBL29612638 | 0.73 | ALDH1A1 (0.63) | ALDH1A1HTTNPSR1MITFHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4434100-A | TRANQUILIZING, ANTICONVULSANTS, ANXIOLYTIC | CIBA-GEIGY CORPORATION (US) | 1984-02-28 | — | — | US | disclosed |
| US-4356176-A | TRANQUILIZERS, ANTICONVULSANT | CIBA-GEIGY CORPORATION (US) | 1982-10-26 | — | — | US | disclosed |
| US-4315926-A | ANXIOLYTIC AGENTS | CIBA-GEIGY CORPORATION (US) | 1982-02-16 | — | — | US | disclosed |