Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | POLA1 | P09884 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3713004 | 0.85 | FAAH (0.60) | TSHRFAAHOXER1ALDH1A1LMNA | |
| SCHEMBL11252256 | 0.83 | FAAH (0.53) | FAAHALDH1A1L3MBTL1 | |
| SCHEMBL50039 | 0.76 | TSHR (1.00) | TSHROXER1ALDH1A1LMNAMEN1 | |
| SCHEMBL21604389 | 0.75 | SLC22A6 (0.50) | TSHRFAAHOXER1ALDH1A1LMNA | |
| SCHEMBL22309941 | 0.75 | TSHR (0.68) | TSHROXER1ALDH1A1LMNAMEN1 | |
| SCHEMBL23113780 | 0.74 | FAAH (0.69) | TSHRFAAHALDH1A1MEN1KMT2A | |
| SCHEMBL8852310 | 0.74 | TSHR (0.65) | TSHROXER1ALDH1A1LMNAMEN1 | |
| Dimethyl Succinate SCHEMBL7262656 | 0.73 | TSHR (0.94) | TSHROXER1ALDH1A1LMNAMEN1 | |
| SCHEMBL8582764 | 0.73 | TSHR (0.94) | TSHROXER1ALDH1A1LMNAMEN1 | |
| SCHEMBL8584321 | 0.73 | TSHR (0.94) | TSHROXER1ALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4489091-A | ESTERASE AND ANTIBODY INHIBITORS | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1984-12-18 | — | — | US | disclosed |
| US-4411911-A | Method of treating hyperlipidemia and inflammation with sulfonate derivatives | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1983-10-25 | — | — | US | disclosed |