Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6264472 | 0.92 | FAAH (0.52) | FAAHALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL21604389 | 0.91 | SLC22A6 (0.50) | FAAHALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11263296 | 0.88 | FAAH (0.47) | FAAHALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11082619 | 0.85 | — | — | |
| SCHEMBL14075859 | 0.85 | — | — | |
| SCHEMBL23113780 | 0.84 | FAAH (0.69) | FAAHALDH1A1SLC22A6HSD17B10 | |
| SCHEMBL11089988 | 0.83 | TSHR (0.58) | FAAHALDH1A1L3MBTL1 | |
| SCHEMBL11084332 | 0.82 | FAAH (0.67) | FAAHALDH1A1SLC22A6HSD17B10 | |
| SCHEMBL11090505 | 0.82 | FAAH (0.67) | FAAHALDH1A1SLC22A6HSD17B10 | |
| SCHEMBL29470896 | 0.82 | FAAH (0.45) | FAAHALDH1A1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0026846-B1 | SUBSTITUTED FULVALENOPHANE DERIVATIVES, THEIR PREPARATION AND THEIR USE | BASF Aktiengesellschaft (DE) | 1982-06-23 | — | — | EP | disclosed |
| US-4298751-A | Cyclically substituted fulvalenophanes | BASF AKTIENGESELLSCHAFT (DE) | 1981-11-03 | — | — | US | disclosed |
| EP-0026846-A1 | Substituted fulvalenophane derivatives, their preparation and their use | BASF Aktiengesellschaft (DE) | 1981-04-15 | — | — | EP | disclosed |