Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 6/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11099000 | 0.71 | LMNA (0.43) | ALDH1A1KMT2AL3MBTL1MEN1TDP1 | |
| SCHEMBL11090124 | 0.71 | HDAC3 (0.32) | KMT2AMEN1TDP1CYP1A2CYP3A4 | |
| SCHEMBL8781208 | 0.70 | TDP1 (0.36) | ALDH1A1TDP1TSHR | |
| SCHEMBL119987 | 0.69 | MCL1 (0.32) | TDP1 | |
| SCHEMBL9326558 | 0.69 | MCL1 (0.32) | TDP1 | |
| SCHEMBL5933883 | 0.69 | MCL1 (0.32) | TDP1 | |
| SCHEMBL11100123 | 0.68 | ALDH1A1 (0.39) | ALDH1A1HPGD | |
| SCHEMBL11060249 | 0.67 | TDP1 (0.34) | ALDH1A1TDP1TSHR | |
| SCHEMBL11060245 | 0.67 | TDP1 (0.34) | ALDH1A1TDP1TSHR | |
| SCHEMBL11884026 | 0.65 | SMN1; SMN2 (0.36) | ALDH1A1SMN1; SMN2KMT2AL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4454134-A | INSECTICIDES, MITICIDES | UNION CARBIDE CORPORATION (US) | 1984-06-12 | — | — | US | disclosed |