Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
| ▸ | NPY2R | P49146 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9425166 | 0.72 | GPR35 (0.60) | GPR35 | |
| SCHEMBL3979968 | 0.72 | KDM4E (0.45) | KDM4ETDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL11090377 | 0.68 | DAO (0.41) | GPR35KDM4ETDP1ALDH1A1HPGD | |
| SCHEMBL5879665 | 0.66 | KDM4E (0.34) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL7698120 | 0.65 | MEN1 (0.43) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL87871 | 0.63 | KDM4E (0.65) | KDM4ETDP1ALDH1A1HPGDMEN1 | |
| SCHEMBL8847161 | 0.62 | JAK2 (0.37) | GPR35KDM4ETDP1ALDH1A1HPGD | |
| SCHEMBL27948924 | 0.62 | GPR35 (0.66) | GPR35PKMCYP1A2CYP2C9 | |
| SCHEMBL30401730 | 0.60 | PARP1 (0.53) | GPR35KDM4ETDP1ALDH1A1HPGD | |
| SCHEMBL2539403 | 0.59 | KDM4E (0.58) | KDM4EALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126970-A2 | Anxiolytic and anti-depressant thienopyridine derivatives | BEECHAM GROUP PLC (GB) | 1984-12-05 | — | — | EP | disclosed |