Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 12/20 | 0.60 |
| ▸ | SRC | P12931 | 4/20 | 0.46 |
| ▸ | PRKACA | P17612 | 3/20 | 0.45 |
| ▸ | PRKACG | P22612 | 3/20 | 0.45 |
| ▸ | PRKACB | P22694 | 3/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27948924 | 0.87 | GPR35 (0.66) | GPR35SRCPRKACAPRKACGPRKACB | |
| SCHEMBL7871830 | 0.79 | GPR35 (0.60) | GPR35SRCPRKACAPRKACGPRKACB | |
| SCHEMBL11784003 | 0.77 | GPR35 (0.66) | GPR35SRCPRKACAPRKACGPRKACB | |
| SCHEMBL14703001 | 0.75 | GPR35 (0.64) | GPR35SRCPRKACAPRKACGPRKACB | |
| SCHEMBL11090367 | 0.72 | GPR35 (0.39) | GPR35 | |
| SCHEMBL31120728 | 0.71 | PRNP (0.61) | GPR35SRCPRKACAPRKACGPRKACB | |
| SCHEMBL7698120 | 0.71 | MEN1 (0.43) | — | |
| SCHEMBL9319718 | 0.70 | KDM4E (0.59) | — | |
| SCHEMBL14702999 | 0.70 | GPR35 (1.00) | GPR35 | |
| SCHEMBL14702927 | 0.69 | GPR35 (1.00) | GPR35SRCPRKACAPRKACGPRKACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0420069-A2 | Heterocyclic hydrazide derivatives of monocyclic beta-lactam antibiotics | E.R. SQUIBB & SONS, INC. (US) | 1991-04-03 | — | — | EP | claimed |
| US-5318963-A | Heterocyclic hydrazide derivatives of monocyclic β-lactam antibiotics | E. R. SQUIBB & SONS, INC. (US) | 1994-06-07 | — | — | US | disclosed |
| EP-0420069-A2 | Heterocyclic hydrazide derivatives of monocyclic beta-lactam antibiotics | E.R. SQUIBB & SONS, INC. (US) | 1991-04-03 | — | — | EP | disclosed |