Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene SCHEMBL11094555 | 0.97 | OPRM1 (0.36) | OPRM1OPRK1OPRD1SLC6A2SLC6A4 | |
| SCHEMBL11557913 | 0.85 | OPRM1 (0.43) | OPRM1OPRK1OPRD1SLC6A2SLC6A4 | |
| SCHEMBL11090344 | 0.84 | OPRM1 (0.45) | OPRM1OPRK1OPRD1SLC6A2SLC6A4 | |
| SCHEMBL11074012 | 0.83 | OPRM1 (0.43) | OPRM1OPRK1OPRD1SLC6A2SLC6A4 | |
| Ethylene SCHEMBL11099465 | 0.83 | OPRM1 (0.42) | OPRM1OPRK1OPRD1SLC6A2SLC6A4 | |
| SCHEMBL11094528 | 0.83 | OPRM1 (0.42) | OPRM1OPRK1OPRD1SLC6A2SLC6A4 | |
| SCHEMBL11622459 | 0.81 | OPRM1 (0.48) | OPRM1OPRK1OPRD1SLC6A2SLC6A4 | |
| Ethylene SCHEMBL11094116 | 0.81 | OPRM1 (0.43) | OPRM1OPRK1OPRD1SLC6A2SLC6A4 | |
| SCHEMBL11092425 | 0.81 | CYP3A4 (0.38) | OPRM1MEN1KMT2AOPRL1 | |
| SCHEMBL11068638 | 0.81 | OPRM1 (0.52) | OPRM1OPRD1SLC6A4OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460604-A | ANALGESICS, NARCOTIC ANTAGONIST | THE UPJOHN COMPANY (US) | 1984-07-17 | — | — | US | disclosed |
| US-4180584-A | ANALGESIC; NARCOTIC ANTAGONIST | THE UPJOHN COMPANY (US) | 1979-12-25 | — | — | US | disclosed |
| US-4065573-A | ANALGESICS | THE UPJOHN COMPANY (US) | 1977-12-27 | — | — | US | disclosed |