Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GRM6 | O15303 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11095573 | 0.86 | CA12 (0.45) | ALOX5MAOBALDH1A1NPSR1MEN1 | |
| SCHEMBL11088637 | 0.85 | ALDH1A1 (0.51) | ALOX5HPGDALDH1A1MAPTKDM4E | |
| SCHEMBL11092361 | 0.81 | TNKS (0.50) | HPGDMAOBALDH1A1KDM4EPDE4B | |
| SCHEMBL11089533 | 0.81 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL11085446 | 0.79 | MEN1 (0.67) | HPGDALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL11088040 | 0.79 | MAOB (0.54) | ALOX5MAOBALDH1A1KMT2AMAPT | |
| SCHEMBL31688015 | 0.77 | GRM6 (0.53) | ALOX5HPGDALDH1A1NPSR1MEN1 | |
| SCHEMBL68855 | 0.77 | HDAC4 (0.53) | MAOBALDH1A1MAPTKDM4EL3MBTL1 | |
| SCHEMBL11085395 | 0.77 | HPGD (0.49) | ALOX5HPGDALDH1A1NPSR1MEN1 | |
| SCHEMBL11079810 | 0.75 | AKR1B1 (0.53) | MAOBALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4471129-A | ANTIHISTAMINES | LILLY INDUSTRIES LIMITED (GB) | 1984-09-11 | — | — | US | disclosed |
| US-4448787-A | ANTIALLERGENS | LILLY INDUSTRIES LIMITED (GB) | 1984-05-15 | — | — | US | disclosed |
| US-4304728-A | 2,6-DIHYDROXY-2,5-HEXADIENOIC ACID DERIVATIVES, ANTIHISTAMINE INTERMEDIATES | LILLY INDUSTRIES LIMITED (GB) | 1981-12-08 | — | — | US | disclosed |