Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.49 |
| ▸ | FEN1 | P39748 | 1/20 | 0.49 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | GABRP | O00591 | 1/20 | 0.45 |
| ▸ | GABRD | O14764 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11088144 | 0.83 | AKR1C3 (0.49) | MEN1KMT2AALDH1A1NPSR1MAPT | |
| SCHEMBL29352723 | 0.80 | ALDH1A1 (1.00) | MEN1KMT2AALDH1A1NPSR1MAPT | |
| SCHEMBL4987351 | 0.80 | ALDH1A1 (1.00) | MEN1KMT2AALDH1A1NPSR1MAPT | |
| SCHEMBL11090522 | 0.79 | ALOX5 (0.48) | MEN1KMT2AALDH1A1NPSR1MAPT | |
| SCHEMBL11095595 | 0.79 | PRKDC (0.52) | MEN1KMT2AALDH1A1NPSR1MAPT | |
| SCHEMBL1176530 | 0.78 | ALDH1A1 (0.58) | MEN1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL11084251 | 0.74 | NPC1 (0.54) | ALDH1A1RAB9ALMNAERCC5FEN1 | |
| SCHEMBL11091374 | 0.72 | MEN1 (0.52) | MEN1KMT2AALDH1A1NPSR1MAPT | |
| SCHEMBL70569 | 0.71 | KDM4E (0.52) | KMT2AALDH1A1MAPTSMN1; SMN2HPGD | |
| SCHEMBL1008973 | 0.70 | MEN1 (0.60) | MEN1KMT2AALDH1A1NPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4471129-A | ANTIHISTAMINES | LILLY INDUSTRIES LIMITED (GB) | 1984-09-11 | — | — | US | disclosed |
| US-4448787-A | ANTIALLERGENS | LILLY INDUSTRIES LIMITED (GB) | 1984-05-15 | — | — | US | disclosed |
| US-4304728-A | 2,6-DIHYDROXY-2,5-HEXADIENOIC ACID DERIVATIVES, ANTIHISTAMINE INTERMEDIATES | LILLY INDUSTRIES LIMITED (GB) | 1981-12-08 | — | — | US | disclosed |