Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 2/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.46 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.46 |
| ▸ | PSMD12 | O00232 | 1/20 | 0.46 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.46 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.46 |
| ▸ | PSMD3 | O43242 | 1/20 | 0.46 |
| ▸ | PSMC3 | P17980 | 1/20 | 0.46 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.46 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.46 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.46 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.46 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.46 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.46 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.46 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.46 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.46 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22526010 | 0.90 | PSMB11 (0.49) | SYKCTSLPSMB11PSMD11PSMD12 | |
| SCHEMBL10042737 | 0.90 | KLKB1 (0.55) | CTSLPSMB11PSMD11PSMD12PSMD14 | |
| SCHEMBL13607250 | 0.89 | TAS1R3 (0.52) | SYKPSMB11PSMD11PSMD12PSMD14 | |
| SCHEMBL1109059 | 0.89 | SYK (0.47) | SYKCTSL | |
| SCHEMBL1109062 | 0.87 | CTSL (0.50) | SYKCTSLPSMB11PSMD11PSMD12 | |
| SCHEMBL10042739 | 0.86 | ATM (0.53) | — | |
| SCHEMBL1109061 | 0.85 | CHRM2 (0.48) | SYKPSMB11PSMD11PSMD12PSMD14 | |
| SCHEMBL10042643 | 0.84 | GRB2 (0.47) | SYKCTSLPSMB11PSMD11PSMD12 | |
| SCHEMBL10042652 | 0.84 | GRB2 (0.47) | SYKCTSLPSMB11PSMD11PSMD12 | |
| SCHEMBL31248331 | 0.83 | PSMB8 (0.50) | PSMB1PSMB8PSMB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153596-B2 | Use of SH2 STAT3/STAT1 peptidomimetics as anticancer drugs | UNIVERSITY OF SOUTH FLORIDA (US) | 2012-04-10 | — | — | US | disclosed |
| US-20090318367-A1 | Use of SH2 STAT3/STAT1 Peptidomimetics as Anticancer Drugs | UNIVERSITY OF SOUTH FLORIDA (US) | 2009-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318367-A1 | Use of SH2 STAT3/STAT1 Peptidomimetics as Anticancer Drugs | STAT3, STAT1, STAT4 | SYK 188/4885CTSL 2723/4885PSMB11 1497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.