Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11083484 | 0.88 | TSHR (0.44) | TSHRKMT2AAPOBEC3AAPOBEC3GCHRNA7 | |
| SCHEMBL16155136 | 0.79 | RAB9A (0.57) | RAB9AKDM4ENPC1SMN1; SMN2APOBEC3A | |
| SCHEMBL10730857 | 0.79 | RAB9A (0.57) | RAB9AKDM4ENPC1SMN1; SMN2APOBEC3A | |
| SCHEMBL16072777 | 0.79 | RAB9A (0.57) | RAB9AKDM4ENPC1SMN1; SMN2APOBEC3A | |
| SCHEMBL10729081 | 0.78 | RAB9A (0.48) | RAB9AKDM4ENPC1SMN1; SMN2TSHR | |
| SCHEMBL11092222 | 0.77 | ABCB1 (0.40) | TSHRKMT2AAPOBEC3AAPOBEC3GCHRNA7 | |
| SCHEMBL16077026 | 0.75 | RAB9A (0.46) | RAB9AKDM4ENPC1SMN1; SMN2TSHR | |
| SCHEMBL16155139 | 0.75 | RAB9A (0.46) | RAB9AKDM4ENPC1SMN1; SMN2TSHR | |
| SCHEMBL16072769 | 0.75 | RAB9A (0.46) | RAB9AKDM4ENPC1SMN1; SMN2TSHR | |
| SCHEMBL11086753 | 0.74 | BCHE (0.35) | TSHRKMT2AAPOBEC3AAPOBEC3GCHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4479966-A | 6,9-Methano-PGI2 analogues | ONO PHARMACEUTICAL COMPANY, LTD. (JP) | 1984-10-30 | — | — | US | disclosed |