Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.38 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16072769 | 1.00 | RAB9A (0.46) | RAB9AKDM4ENPC1SMN1; SMN2TSHR | |
| SCHEMBL16077026 | 1.00 | RAB9A (0.46) | RAB9AKDM4ENPC1SMN1; SMN2TSHR | |
| SCHEMBL10729081 | 0.90 | RAB9A (0.48) | RAB9AKDM4ENPC1SMN1; SMN2TSHR | |
| SCHEMBL16077039 | 0.87 | GAA (0.39) | TSHRGAAKMT2AABCB1CHRM2 | |
| SCHEMBL16072779 | 0.87 | GAA (0.39) | TSHRGAAKMT2AABCB1CHRM2 | |
| SCHEMBL1584062 | 0.79 | GAA (0.52) | TSHRGAAKMT2A | |
| SCHEMBL9687625 | 0.76 | GAA (0.37) | TSHRGAACHRM2CHRM4CHRM1 | |
| SCHEMBL16077036 | 0.75 | BCHE (0.31) | BCHE | |
| SCHEMBL11090666 | 0.75 | RAB9A (0.48) | RAB9AKDM4ENPC1SMN1; SMN2TSHR | |
| SCHEMBL16077037 | 0.75 | BCHE (0.31) | BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014164886-A1 | PROSTANOID RECEPTOR AGONIST COMPOUNDS AND THEIR USE | ALLERGAN, INC. (US) | 2014-10-09 | — | — | WO | disclosed |