SCHEMBL11090673

SCHEMBL11090673

CCCOc1cc2c(cc1Cc1ccc(OC)cc1)OCO2

nearest known ligand 0.81

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
EDNRA P25101 3/20 0.43
EDNRB P24530 2/20 0.43
ALDH1A1 P00352 1/20 0.42
CASP3 P42574 1/20 0.41
SENP7 Q9BQF6 1/20 0.41
HTR2A P28223 1/20 0.41
HTR2C P28335 1/20 0.41
HTR2B P41595 1/20 0.41
RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11091581 0.95 HTR2A (0.43) ALDH1A1CASP3SENP7HTR2AHTR2C
SCHEMBL11085728 0.89 KMT2A (0.49) ALDH1A1
SCHEMBL11084898 0.86 MEN1 (0.42) ALDH1A1
SCHEMBL11091308 0.86 ALDH1A1 (0.40) ALDH1A1
SCHEMBL11086620 0.86 HTR2A (0.48) ALDH1A1HTR2AHTR2CHTR2B
SCHEMBL11091375 0.83 CYP1A2 (0.42) ALDH1A1CASP3SENP7HTR2AHTR2C
SCHEMBL11080627 0.81 ALDH1A1 (0.49) ALDH1A1HTR2AHTR2CHTR2BRAB9A
SCHEMBL11090689 0.80 CYP1A2 (0.44) ALDH1A1
SCHEMBL11081351 0.76 CYP1A2 (0.55) ALDH1A1RAB9A
SCHEMBL30885583 0.76 CYP1A2 (0.55) ALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4482728-A ANTIFERTILITY AGENTS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1984-11-13 US disclosed
US-4357344-A Polybutylbenzylphenols and benzyl-3,4-methylenedioxybenzenes in insect population control THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1982-11-02 US disclosed
US-4342777-A GROWTH INHIBITOR FOR MOSQUITO LARVAE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1982-08-03 US disclosed