Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11086620 | 0.87 | HTR2A (0.48) | ALDH1A1KMT2A | |
| SCHEMBL11091375 | 0.84 | CYP1A2 (0.42) | CYP1A2CYP3A4CYP2D6CYP2C9ALOX15 | |
| SCHEMBL11085728 | 0.82 | KMT2A (0.49) | ALDH1A1KMT2AGAAMAPT | |
| SCHEMBL11084898 | 0.82 | MEN1 (0.42) | CYP1A2CYP3A4CYP2D6CYP2C9ALOX15 | |
| SCHEMBL11090673 | 0.80 | EDNRA (0.43) | ALDH1A1 | |
| SCHEMBL11091581 | 0.80 | HTR2A (0.43) | CYP3A4ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL11081351 | 0.77 | CYP1A2 (0.55) | CYP1A2CYP3A4CYP2D6CYP2C9ALOX15 | |
| SCHEMBL30885583 | 0.77 | CYP1A2 (0.55) | CYP1A2CYP3A4CYP2D6CYP2C9ALOX15 | |
| SCHEMBL8785648 | 0.77 | BRS3 (0.50) | ALDH1A1 | |
| SCHEMBL11080627 | 0.76 | ALDH1A1 (0.49) | CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482728-A | ANTIFERTILITY AGENTS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1984-11-13 | — | — | US | disclosed |
| US-4357344-A | Polybutylbenzylphenols and benzyl-3,4-methylenedioxybenzenes in insect population control | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1982-11-02 | — | — | US | disclosed |
| US-4342777-A | GROWTH INHIBITOR FOR MOSQUITO LARVAE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1982-08-03 | — | — | US | disclosed |