Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | CPT2 | P23786 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | ACACA | Q13085 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11090499 | 1.00 | FFAR1 (0.32) | FFAR1CPT2TDP1ACACBACACA | |
| SCHEMBL11083812 | 1.00 | FFAR1 (0.32) | FFAR1CPT2TDP1ACACBACACA | |
| SCHEMBL28162199 | 0.89 | FDPS (0.36) | — | |
| SCHEMBL28162201 | 0.89 | FDPS (0.36) | — | |
| SCHEMBL18124683 | 0.87 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL18124692 | 0.87 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL18124708 | 0.84 | ALDH1A1 (0.35) | — | |
| SCHEMBL18124709 | 0.84 | ALDH1A1 (0.35) | — | |
| SCHEMBL18124703 | 0.84 | ALDH1A1 (0.35) | — | |
| SCHEMBL1356446 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4454145-A | Nicotinates of alkanediols having hypolipidaemic activity and pharmaceutical compositions containing them | ALFA FARMACEUTICI S.P.A. (IT) | 1984-06-12 | — | — | US | disclosed |
| EP-0064286-A2 | New derivatives of alkanediols having hypolipidaemic activity, methods for their preparation and pharmaceutical compositions containing them | ALFA FARMACEUTICI S.p.A. (IT) | 1982-11-10 | — | — | EP | disclosed |