Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.47 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.46 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.46 |
| ▸ | SGPL1 | O95470 | 4/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.43 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.43 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11089390 | 1.00 | LPAR5 (0.47) | LPAR5LPAR3LPAR1LPAR2SGPL1 | |
| SCHEMBL11077167 | 0.85 | LPAR5 (0.57) | LPAR5LPAR3LPAR1LPAR2SGPL1 | |
| SCHEMBL11083665 | 0.84 | LPAR3 (0.46) | LPAR5LPAR3LPAR1LPAR2SGPL1 | |
| SCHEMBL11090225 | 0.82 | ENPP2 (0.57) | LPAR5LPAR3LPAR1LPAR2SGPL1 | |
| SCHEMBL11127519 | 0.81 | FABP3 (0.51) | — | |
| SCHEMBL11126107 | 0.81 | FABP3 (0.51) | — | |
| Phosphoric Acid SCHEMBL11089388 | 0.80 | CES1 (0.42) | LPAR3LPAR2SMPD1 | |
| Phosphoric Acid SCHEMBL11090703 | 0.80 | CES1 (0.42) | LPAR3LPAR2SMPD1 | |
| SCHEMBL8976731 | 0.78 | CA2 (0.54) | — | |
| SCHEMBL29068432 | 0.77 | SGPL1 (0.55) | LPAR5LPAR3LPAR1LPAR2SGPL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4444766-A | ANTITUMOR | BOEHRINGER MANNHEIM GMBH (DE) | 1984-04-24 | — | — | US | disclosed |