Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17707781 | 0.86 | TSHR (0.53) | HPGDTSHRMAPTPOLBMEN1 | |
| SCHEMBL11092742 | 0.83 | HPGD (0.56) | HPGDTSHRMEN1MAPK1KMT2A | |
| SCHEMBL23294948 | 0.82 | TSHR (0.51) | TSHRMAPTPOLBMEN1MAPK1 | |
| SCHEMBL29588719 | 0.82 | TSHR (0.51) | TSHRMAPTPOLBMEN1MAPK1 | |
| SCHEMBL11089521 | 0.81 | CXCL8 (0.47) | HPGDMAPTMEN1MAPK1KMT2A | |
| SCHEMBL6656676 | 0.77 | MEN1 (0.68) | HPGDTSHRMAPTPOLBMEN1 | |
| SCHEMBL18285205 | 0.77 | TSHR (0.56) | HPGDTSHRMAPTPOLBMEN1 | |
| SCHEMBL3789796 | 0.76 | ALDH1A1 (0.64) | HPGDTSHRMAPTPOLBMEN1 | |
| SCHEMBL3405509 | 0.76 | ALDH1A1 (0.46) | HPGDMAPTPOLBMEN1KMT2A | |
| SCHEMBL17707783 | 0.76 | ALDH1A1 (0.55) | HPGDTSHRMAPTPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4472433-A | Phenoxyphenyl acetic acids and their medicinal use | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-09-18 | — | — | US | disclosed |
| EP-0008226-B1 | PHENYL-ALKANOIC ACID DERIVATIVES, THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-11-02 | — | — | EP | disclosed |
| EP-0008226-A2 | Phenyl-alkanoic acid derivatives, the preparation thereof and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-02-20 | — | — | EP | disclosed |